21c Museum Hotel St. Louis

1528 Locust Street
St. Louis, MO 63103
United States



173 room boutique hotel that features an art museum surrounded by meeting and event space showcasing rotating curated exhibitions. Amenities include a beautiful Fitness and Spa with a steam room, full size pool, sauna, whirlpool, and treatment rooms. Idol Wolf and Good Press Café are available for your dining pleasures!

Exclusive Amenities

  • Full Breakfast for up to two guests
  • $50 USD Food & Beverage Credit, once per stay
The following amenities are subject to availability at the time of check-in/departure:
  • Early Check-In
  • Late Check-Out
  • Upgrade

Check In: 4:00 pm
Check Out: 11:00 pm

Information, amenities and pricing is subject to change without notice. While we do our very best to ensure that information and pricing appearing in this website is complete and accurate, we cannot be responsible for incomplete and inaccurate representations, which may or may not be under our control. In the event of an error, misrepresentation or omission, we reserve the right to make a correction. Note that during these unprecedented times, local government regulations may inhibit hotels from providing normal facilities and services, limiting the ability to provide the listed amenities/benefits.